Frederick Sanger & Colleagues Conduct the First Whole Genome Shotgun Sequence

In 1982 British biochemist Frederick Sanger and colleagues sequenced the entire genome of bacteriophage lambda using a random shotgun technique. This was the first whole genome shotgun (WGS) sequence.

Sanger, et al “Nucleotide Sequence of Bacteriophage Lambda,” J. Mol. Biol. 162 (1982) 729-73.