A: Esslingen am Neckar, Baden-Württemberg, Germany
The first printed book on wine, Von Bewahrung und Bereitung der Weine, by Catalan physician Arnald of Villanova, was translated from the Latin by Wilhelm von Hirnkofen, and published in Esslingen, Germany by Konrad Fyner in October 1478. It discussed the value of wine in diet and as a medication.
In 1943 medical historian Henry Sigerist issued a facsimile of the first edition, with an English translation and introduction, entitled The Earliest Printed Book on Wine.
♦ In November 2013 a digital facsimile of the first printed edition was available at the Bayerische Staatsbibliothek, München at this link.