![First leaf of the first book printed in Venice, Cicero, Epistolae ad familiares by Johannes de Spira, [before September 18,] 1469. From the copy in the Biblioteca Nazionale Marciana, Venice. This is ISTC ic00504000. The ISTC also describes a variant issued presumably on or around the same date by Spira: ISTC ic00505000. First leaf of the first book printed in Venice, Cicero, Epistolae ad familiares by Johannes de Spira, [before September 18,] 1469. From the copy in the Biblioteca Nazionale Marciana, Venice. This is ISTC ic00504000. The ISTC also describes a variant issued presumably on or around the same date by Spira: ISTC ic00505000.](http://historyofinformation.com/images/Screen_Shot_2019-07-19_at_3.02.07_PM.png)
First leaf of the first book printed in Venice, Cicero, Epistolae ad familiares by Johannes de Spira, [before September 18,] 1469. From the copy in the Biblioteca Nazionale Marciana, Venice. This is ISTC ic00504000. The ISTC also describes a variant issued presumably on or around the same date by Spira: ISTC ic00505000.