In 1598 physician Israel Spach issued Nomenclator scriptorum philosophicorum atque philologicorum in Strassburg. Covering the works of over 4,000 authors arranged under 400 subject headings, including esoteric subjects like gladiatorial combat, glory, and sobriety, with an emphasis on contemporary writers, this was the most significant subject bibliography of the sixteenth century. It became a model for subsequent subject bibliographies.
Breslauer & Folter, Bibliography: Its History and Development  no. 39.