A: Altstadt, Mainz, Rheinland-Pfalz, Germany
With his edition of Pope Pius II's Bulla Cruciata contra Turcos in 1463 printer Peter Schöffer of Mainz issued the first publication with a separate printed title page. It is thought that this title page was an experiment, as "the Aschaffenburg copy has a title-page in Psalter type; the Paris copy has a woodcut title; the Musée Condé copy has a title in MS" (ISTC no. ip00655750 citing two copies in France, three in Germany and one in Holland).
• The separate title page did not begin to come into widespread use in printed books until the end of the 15th century.
In November 2013 a digital facsimile was available from HAB Wolfenbüttel at this link.
Smith, The Title-Page, its Early Development 1460-1510 (2000) 38-40.