On November 26, 1761 English physician Frank Nicholls's "Observations concerning the Body of his late Majesty, October 26, 1760" was read before the Royal Society. This paper, in which Nicholls described and illustrated a rupture of the right ventricle he discovered at the autopsy of the late George II, was published in Philosophical Transactions Vol. 52, Pt 1, 265-272. It was illustrated with two folding plates of the heart engraved by J. Mynde and printed in two colors (brown and sanguine). These were probably the first color-printed plates in a major scientific periodical.